Cogan's Syndrome in Patients With Inflammatory Bowel Disease – A Case Series

Stephan R. Vavricka, Thomas Greuter, Michael Scharl, Gerassimos Mantzaris, Ariella B. Shitrit, Rafal Filip, Konstantinos Karmiris, Christoph K. Thoeringer, Hubert Boldys, Anne V. Wewer, Henit Yanai, Cristina Flores (+4 others)
2015 Journal of Crohn's & Colitis  
BACKGROUND: Cogan's syndrome (CSy) is a very rare autoimmune disorder, mainly affecting the inner ear and the eye, and is associated with inflammatory bowel disease (IBD). METHODS: This was a European Crohn's and Colitis Organisation (ECCO) retrospective observational study, performed as part of the CONFER project. A call to all ECCO members was made to report concomitant CSy and inflammatory bowel disease (IBD) cases. Clinical data were recorded in a standardized questionnaire. RESULTS: This
more » ... ternational case series reports on 22 concomitant CSy-IBD cases from 14 large medical centres. Mean duration of IBD until diagnosis of CSy was 8.7 years (range 0.0-38.0) and mean age at CSy diagnosis was 44.6 years (range 9.0-67.0).
doi:10.1093/ecco-jcc/jjv128 pmid:26188351 fatcat:iqjpibvpbncblntaavaeyipxr4