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We report here a multiprotein blind test of a computer method to predict native protein structures based solely on an all-atom physics-based force field. We use the AMBER 96 potential function with an implicit (GB/SA) model of solvation, combined with replica-exchange molecular-dynamics simulations. Coarse conformational sampling is performed using the zipping and assembly method (ZAM), an approach that is designed to mimic the putative physical routes of protein folding. ZAM was applied to thedoi:10.1016/j.bpj.2008.11.009 pmid:19186130 pmcid:PMC2716649 fatcat:thj6xkyiyvfitcrrsf6uyibih4