Progress in the Theory and Practice of Medicine

1911 Boston Medical and Surgical Journal  
The apparent improvement, after the administration of antitoxin, was probably coincidental with the successful manufacture of antibodies in sufficient numbers to protect. The most striking feature of this case, aside from the unusual situation of the lesion, is that the offending organism, usually non-pathogenic, was in this instance strongly pathogenic.
doi:10.1056/nejm191104271641707 fatcat:7ghlwiz5qbhmbi7cw5tqvgm3me