Spironolactone-Induced Agranulocytosis: A Case Report

Shu-Hwa Hsiao, May-Ying Hsu, Yih-Jyh Lin, Ta-Jen Wu
2003 Kaohsiung Journal of Medical Sciences  
A 43-year-old woman with liver cirrhosis and hepatocellular carcinoma was admitted for the chief problem of ascites. Laboratory data revealed a leukocyte count of 3.8 × 10 9 /L on the second day of admission. Spironolactone was prescribed for diuresis beginning on the third day. Routine blood tests on the tenth day disclosed marked leukopenia (1.8 ×
doi:10.1016/s1607-551x(09)70509-1 pmid:14658487 fatcat:mglwbxiamzecnc23tshe5knmyu