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Identification of a substrate site for liver transglutaminase on the aminopropeptide of type III collagen
1987
Journal of Biological Chemistry
Preserved Fulltext
The aminopropeptide of type III collagen incorporates [3H]putrescine in the presence of liver transglutaminase, and the change in incorporation with concentration indicates one binding site on each of the Mr = 15,000 subunits of the peptide. At low concentrations the incorporation was comparable to that of dimethyl casein and much greater than actin or fibrinogen. Cleavage and Edman degradation of the aminopropeptide identified the major putrescine-binding site as glutamine in position 14. The
pmid:2879837
fatcat:dqmgtla32veevapmbw2rioms6q