STUDY OF THE CELLULAR COMPONENT OF IMMUNE SYSTEM IN CASES OF TRAUMATIC MANDIBULAR FRACTURE IN PATIENTS OF DIFFERENT PSYCHOSOMATIC PERSONALITY TYPES

Ya.P. Nahirniy, V. L. Fesyk
2017 Ukraïnsʹkij stomatologìčnij alʹmanah  
The high risk of purulent complications in treatment of traumatic open mandibular fractures, which frequency is 35-41,0%, is caused by the presence of a significant amount of microflora in an oral cavity, mucous membrane ruptures in the area of fracture and also significantly by body defences state. According to the recent literature, it is established that during treatment of patients with traumatic mandibular fractures their psychosomatic state influences on the development of purulent
more » ... ations. This influence occurs due to different degree of the effect of psyche on immune system that is crucial in purulent complications development. However, there are no researches in immune perturbations depending on psychosomatic type of personality of patients with mandibular fractures. The aim of the research was to study functional disorders of immune system cellular component in patients with traumatic mandibular fractures depending on psychosomatic type of personality. Material and Methods The dynamics of immune status rate was studied in 60 male patients diagnosed with traumatic unilateral open mandibular fractures in the area of a corner, average age was 25.2±5.0 years old. The patients were divided into two groups: extraverts (the 1st group, 36 individuals), introverts (the 2nd group, 24 individuals) according to the Eysenck's classification. The researches were conducted on the 1st, 3rd, 7th day after a trauma. Identification of T- and B-lymphocytes was performed by means of Status monoclonal antibodies. The quantity of subpopulations CD3+-, CD4+-, CD8+-, CD16+-lymphocytes was evaluated in percent. Results and Discussion The results of the research of a cellular component of immunity proved the decrease in relative quantity of the general pool of T-lymphocytes (CD3+) in both studied groups. The tendencies of their quantitative changes were similar. However, in the patients of the 1st group (the extraverts) on the 7th day of the research, a complete restitution of the quantity of T-lymphocytes (CD3+) [...]
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