The aim of the study is to investigate a vasomotor function of patients with COPD against the development of acute myocardial infarction (AMI) with an elevation of the ST segment of the electrocardiogram. The brachial artery reactivity was studied in 42 patients with COPD during the course of treatment in the Amur Regional Clinical Hospital. All the patients were divided into two groups: 1st group (22 patients) with COPD and AMI with an elevation of the ST segment; 2nd group (20 patients) -

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... moderate COPD. The control group included 15 healthy people without cardiovascular diseases and respiratory pathology. The study was done at the ultrasonic device Toshiba Aplio XG with the linear probe of 10MHz using the method by D.S.Celermajer et al. (1992). The following results were obtained: the majority of COPD patients demonstrate vasomotor endothelial dysfunction that can cause atherosclerosis; in case of COPD and AMI comorbidity an endothelial dysfunction redoubles; development of AMI coincides with the "peak" of endothelial dysfunction determined with the help of endothelium-dependent vasodilatation. The method of endothelial dysfunction determination is non-invasive and accurate to predict cardiovascular diseases in COPD patients.