This paper presents a novel method for the energy optimization of multi-carrier energy systems. The presented method combines an adaptive neuro-fuzzy inference system, to model and forecast the power demand of a plant, and a genetic algorithm to optimize its energy flow taking into account the dynamics of the system and the equipment's thermal inertias. The objective of the optimization algorithm is to satisfy the total power demand of the plant and to minimize a set of optimization criteria,

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... rmulated as energy usage, monetary cost and environmental cost. The presented method has been validated under real conditions in the car manufacturing plant of SEAT in Spain in the framework of an FP7 European research project.