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Thyroid hormones are important mediators of growth and development in vertebrates and act by binding to a specific family of thyroid receptors (TRs). The TRs belong to the nuclear receptor superfamily, with two conserved regions, a DNA binding domain and a ligand binding domain (LBD). We recently demonstrated the presence of four TR subtypes in goldfish, two with complete DNA binding domains and LBDs (TR␣-1 and TR␤) and two novel forms including a transcript resembling TR␣ with variation in thedoi:10.1210/en.2008-0107 pmid:18511506 fatcat:s6nyfhwvwze6pmzlntovbutrs4