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The objective of the ACGT (Advancing Clinico-Genomic Trials on Cancer: Open Grid Services for improving Medical Knowledge Discovery, www.eu-acgt.org) project that has recently concluded successfully was the development of a semantically rich infrastructure facilitating seamless and secure access and analysis, of multi-level clinical and genomic data enriched with high-performing knowledge discovery operations and services in support of multicentric, post-genomic clinical trials. In this paperdoi:10.1016/j.procs.2011.04.119 fatcat:ls5emmpmrrfwnhnkscbpazorge