CYTOHISTOLOGICAL CORRELATIVE STUDY OF BREAST LESIONS
English

Kanchana P V N, Ramalaxmi P V B, Prasada Reddy K, Raiza D
2015 Journal of Evolution of Medical and Dental Sciences  
BACKGROUND: Breast lump is fairly common complaint in females for which patient seeks medical advice and becomes anxious about the diagnosis. Quick diagnosis by Fine needle aspiration cytology (FNAC) relieves patient's anxiety and assists in their pre-operative management and overall treatment. AIMS: To study the cytological spectrum of breast lesions in correlation with histological appearances to evaluate the utility of FNAC in the diagnosis of palpable breast lesions. MATERIALS AND METHODS:
more » ... RIALS AND METHODS: Total of 180 cases were studied by FNAC of which 42 cases specimen was received for histopathology examination (HPE). Diagnostic accuracy was studied by statistical analysis. RESULTS: In this study of 42 cases of correlation, maximum cases were obtained for fibroadenoma followed by malignancy. FNAC diagnosis was consistent with HPE in 41 cases and inconsistent in one case. CONCLUSION: FNAC can reliably distinguish between benign and malignant conditions, neoplastic and non-neoplastic conditions. The result compared with other studies substantiate the findings of the series that FNAC of breast is a sensitive and specific modality that assist in diagnosis and management of breast lesions. KEYWORDS: FNAC; breast lesions; HPE. INTRODUCTION: Lump breast is a fairly common complaint for which patient seeks medical advice and becomes anxious about the diagnosis. FNAC is an important diagnostic procedure used to evaluate breast lesions and to assist in their pre-operative management and overall therapy. In addition to the initial diagnosis, FNAC is of value in staging the disease, documenting recurrence and identifying tumor transformation. It has acquired a very important role in the diagnosis of palpable breast lesions and has largely replaced open biopsy, especially frozen sections. It is a simple, inexpensive, minimally invasive method and relatively painless. It provides the diagnosis in a short time and has low risk of complications. There are no contraindications to FNAC of breast lumps. This study aims at correlating the cytological diagnosis and HPE to evaluate sensitivity, specificity and diagnostic accuracy thereby its role in preoperative diagnosis of palpable breast lump and planning proper management. MATERIALS AND METHODS: The present study includes aspiration smears of all cases with breast lump. These cases were referred to the cytology lab in the department of pathology. The total number of aspiration smears done were180 cases. In 42 cases we obtained specimens. After taking consent and relevant history, FNAC was done after local examination. Smears were stained with Haematoxylin and Eosin. Histopathology specimens were examined, sections were given from representative area, processed and stained with Haematoxylin and Eosin. RESULTS: The present study includes 180 cases of FNACs of breast lesions received at the Cytopathology laboratory, during the period January 2010 -June 2012. Breast lesions constituted 11.05% of the total FNACs done during this period.
doi:10.14260/jemds/2015/639 fatcat:2gvaa7keqvg2hfwfssfevub6xa