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Bone marrow-and adult kidney-derived stem/progenitor cells hold promise in the development of therapies for renal failure. Here is reported the identification and characterization of renal multipotent progenitors in human embryonic kidneys that share CD24 and CD133 surface expression with adult renal progenitors and have the capacity for self-renewal and multilineage differentiation. It was found that these CD24 ϩ CD133 ϩ cells constitute the early primordial nephron but progressively disappeardoi:10.1681/asn.2007020210 pmid:17978305 fatcat:sipaui5xgfgn3nsk57tai3wfrm