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Biological actions of lipoic acid associated with sulfane sulfur metabolism
Pharmacological Reports
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This work aimed to investigate the effect of lipoic acid (LA) on sulfane sulfur (S(*)) level and rhodanese activity in rat tissues. In vitro studies conduced so far have indicated that dihydrolipoic acid serves as an S(*) acceptor in the rhodanese-catalyzed S(*) transfer. This study revealed a significant increase in S(*) level and rhodanese activity in the heart, liver and kidney homogenates from rats that had previously been treated intraperitoneally with LA. It demonstrated for the first
pmid:18443384
fatcat:4vty3d3ivbbbzhz22wl5bdtmru