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Synthesis and Study of 1,2,4-Oxadiazolines derivatives and their Antifungal activity
2016
IOSR Journal of Applied Chemistry
Addition of benzonitrileoxide,generatedin situ by the action of triethylamine on benzhydoxamoyl chloride, to 2-hydroxybenzalaniline and its N-phenyl derivatives yielded a mixture of products which was separated into two compounds by fractional crystallization. The major products have been found to be the respective cycloadducts and the minor product was identified as the dimer of the starting nitrile oxide. The cycloadducts have been identified as 1,2,4-oxadiazoline derivatives (Ia-Va) on the
doi:10.9790/5736-0909015254
fatcat:dcgpgvwz6fhwtd5klllk7rbdvi