A series of novel binuclear transition metal complexes was synthesized by reaction of a Schiff base ligand 2-((1-methyl-2-((2-oxo-1,2-dihydro-pyrimidin-4-yl)imino)propylidene)amino)acetic acid) (L a H) derived from 4-amino-1H-pyrimidin-2-one, diacetyl, glycine and the corresponding chloride salt of Cu(II), Ni(II), Co(II) and Zn(II) metals in a 1:1 (metal:ligand) mole ratio. The compounds were characterized by elemental analyses, molar conductance measurements, magnetic moment measurements and

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... rious spectral studies viz. IR, UV-Vis, 1 H-NMR, 13 C-NMR, EPR and ESI-MS. The molar conductance measurements revealed the non-electrolytic nature of the metal complexes. Electronic absorption spectral data, electronic paramagnetic resonance parameters and magnetic moment values revealed an octahedral geometry for the binuclear metal complexes. A cyclic voltammetric study of Ni(II) complex shows a couple of one-electron anodic responses near 0.70 and 1.10 V. The in vitro biological activity of the Schiff base ligand and the binuclear complexes was assessed against bacteria (Staphylococcus aureus, Bacillus subtilis, Escherichia coli and Salmonella typhi) and fungi (Candida albicans and Candida parapsilosis) to ascertain their antibacterial and antifungal properties.