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Limits to the clinical Application of ICSI
Journal of Mammalian Ova Research
Microinsemination is a revolutionary and promising technique for the treatment of severe male infertility, such as severe oligozoospermia, asthenozoospermia, and the case of unexplained unfertilization in which the conventional IVF is ineffective even if semen parameters are normal. Several different microinsemination techniques, such as zona opening [1-3], subzona sperm injection [4, 5], and intracytoplasmic sperm injection (ICSI) , have been introduced. ICSI is considered the mostdoi:10.1274/jmor.17.77 fatcat:ftlpcazz3zehtjlj3itwb6bj7i