ESTs and putative line-specific (broiler and layer) SNPs identified in genes expressed in Gallus gallus pituitary and hypothalamus

Clarissa Sanches da Silva Cassoli, Erika Cirstina Jorge, Mateus Patrício, Helena Javiel Alves, Erik Amazonas de Almeida, Mônica Corrêa Ledur, Luiz Lehmann Coutinho
2007 Genetics and Molecular Biology  
Brazilian poultry industry has reached a high level of development in both meat and egg production as a result of constant technological modernization. Further improvements can be achieved through genomics, but before this can be accomplished, a better understanding of gene expression profiles and nucleotide polymorphisms is necessary. Since animal physiology is directly or indirectly controlled by the pituitary and hypothalamus, the aim of the present work was to identify and analyze genes
more » ... essed in these tissues in chicken lines with different growth potential. Two pituitary and hypothalamus cDNA libraries from 21 day broiler (TT) and layer (CC) chickens lines were constructed and allowed identification of 3,074 unique sequences and 77 single nucleotide polymorphisms (SNPs). The collection of expressed sequence tags (ESTs) and SNPs identified in this study represents an important resource for future studies aimed at identifying genes responsible for growth in chicken.
doi:10.1590/s1415-47572007000600008 fatcat:k7kkxfiwabga7bg342yfmj5c6e