Hidden complexities in the unfolding mechanism of a cytosine-rich DNA strand [article]

Jens Smiatek, Daniel Janssen-Mueller, Rudolf Friedrich, Andreas Heuer
2011 arXiv   pre-print
We investigate the unfolding pathway of a cytosine-rich DNA hairpin structure via Molecular Dynamics simulations. Our results indicate a hidden complexity present in the unfolding process. W e show that this complex behavior arises due to non-stochastic contributions which have an important impact on the description of the dynamics in terms of collective variables.
arXiv:1109.5474v1 fatcat:62upvgqn6vb3xljmqjrq5nouni