necessarily mean syphilis, and that a diagnosis of syph¬ ilis cannot be based on weak and medium inhibitions when they are employed. We hold that weakly positive reactions with syphilitic liver-extract mean nothing but syphilis. Even though it were true that the cholesterin¬ ized antigens give a more delicate reaction and may furnish positive results in cases of syphilis that are neg¬ ative to the syphilitic liver-extract, it is a very much less serious error to overlook an occasional case of

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... ph¬ ilis than to saddle a diagnosis of the disease with all it entails on a patient who does not have syphilis. Considerable harm is being done at present by the use of unreliable non-specific or artificial extracts, in two ways: 1. The marked discrepancies between the results of