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Noradrenergic Excitation of Magnocellular Neurons in the Rat Hypothalamic Paraventricular Nucleus via Intranuclear Glutamatergic Circuits
1998
Journal of Neuroscience
Noradrenergic projections to the hypothalamus play a critical role in the afferent control of oxytocin and vasopressin release. Recent evidence for intrahypothalamic glutamatergic circuits prompted us to test the hypothesis that the excitatory effect of noradrenergic inputs on oxytocin and vasopressin release is mediated in part by local glutamatergic interneurons. The voltage response to norepinephrine (30-300 M) was tested with whole-cell recordings in putative magnocellular neurons of the
doi:10.1523/jneurosci.18-24-10619.1998
pmid:9852597
fatcat:maoqdtslgbbozbznlvd2se6fk4