Lipomas, which are benign adipose tissue tumors, are the most common tumors of mesenchymal origin in humans. Some variants of lipoma have been described according to the type of tissue present. A rare variant consists of a lipoma with osseous or cartilaginous metaplasia. We present the case of a lipoma with chondro-osteoblastic metaplasia of right buttock in a 57-year-old male. He was referred for a painless mass on the right lateral margin of the buttock, and present for about 1 month.

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... resonance images revealed a 12× 8× 4 cm sized mass with secondary degeneration focally, involving deep portion of the right gluteus maximus muscle, and protruded to adductor magnus muscle. T1 weighted images showed signal enhancement within the mass. He underwent complete resection of the tumor. No recurrence was observed after five years follow-up. Lipoma with chondro-osteoblastic metaplasia is extremely rare disease. Here, we report it along with the corresponding literature.