Copper-catalyzed aerobic cascade cycloamination and acyloxylation: a direct approach to 4-acyloxy-1H-pyrazoles

Zhengwei Ding, Qitao Tan, Mingchun Gao, Bin Xu
2015 Organic and biomolecular chemistry  
An efficient copper-catalyzed regioselective olefinic C(sp2)–H bond cycloamination and acyloxylation was developed to give acyloxylated pyrazoles under mild conditions, which combines the formation of the pyrazole skeleton and installation of an acyloxyl group in a single step.
doi:10.1039/c5ob00409h pmid:25785917 fatcat:25x23mm2lzb5zais74sdheoppa