Owing to miniaturisation, dose-depletion, continuous and restrictive liberation of active substances, well established material constancy, the field concerned with advanced nanostructured systems has seen rapid growth in recent years. Nanosponge's invention has become an important step in overcoming the problems of poorly water-soluble drugs which show many traditional formulating complications. Nanosponge is a compact virus sized sponges (250nm-1um) that credibly stuffed by a broad range of

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... ications and travel across the body until it binds with a certain pointed spot and sticks to the exterior and releases the drug in a restrained manner. This review focuses on methods of preparation, nanosponge applications, factors effecting the drug delivery area, characterization of nanosponges. Nanosponges are an essential conveyor that supply active substances as well as therapeutic medicine delivery process in the medicament industry in post-validate clinical trials. These helps to deliver the drugs at the targeted sites without effecting the healthy cells as well as shows less/or no side-effects. Nanosponges review helps to understand the advantages of this new medication method over conventional medication system. By enhancing the solubility of poorly water-soluble drugs these hels to deliver the drugs, orally as well as topically without first pass metabolism. This is the upcoming system of medication. Keywords: Nanosponges, controlled, drug delivery, cyclodextrin based polymer, targeted.