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Air pollution and DNA methylation alterations in lung cancer: A systematic and comparative study
2016
OncoTarget
The lung cancer incidence in the Xuanwei and neighboring region, Yunnan, China, is among the highest in China and is attributed to severe air pollution with high benzo(a)pyrene levels. We systematically and comparatively analyzed DNA methylation alterations at genome and gene levels in Xuanwei lung cancer tissues and cell lines, as well as benzo(a)pyrene-treated cells and mouse samples. We obtained a comprehensive dataset of genome-wide cytosine-phosphate-guanine island methylation in air
doi:10.18632/oncotarget.13622
pmid:27901495
pmcid:PMC5352062
fatcat:npbar6bzd5hzvmepeebzs47nsu