Immunopotentiating activity of abrin, a lectin from Abrus precatorius Linn

V Ramnath, Girija Kuttan, Ramadasan Kuttan
2002 Indian journal of experimental biology  
A non-toxic dose of abrin, (1.25 microg/kg body wt) consecutively for five days in normal mice stimulated specific humoral responses. A noticeable increase was observed in total leucocyte count, lymphocytosis, weights of spleen and thymus, circulating antibody titre, antibody forming cells, bone marrow cellularity and alpha-esterase positive bone marrow cells. The results suggest that abrin can potentiate the humoral immune response of the host.
pmid:12597021 fatcat:lrkerh6rzfd2jnyokbyurxegae