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Fatigue in multiple sclerosis: The role of thalamus
2019
Multiple Sclerosis
Fatigue is very common in multiple sclerosis (MS) and is often considered as its most disabling symptom. Over the last 20 years, an increasing number of studies have evaluated the pathogenetic bases of MS-related fatigue. Converging evidence from neurophysiology and neuroimaging research suggests that a dysfunction in a cortico-subcortical pathway, centered on thalamus, is involved in the pathogenesis of fatigue. However, type and significance of such dysfunction remain unknown, and some
doi:10.1177/1352458519851247
pmid:31138052
fatcat:ijepq5qs5vfbnn2saibb3wfmuy