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Mass spectrometry is a particularly useful technology for the rapid and robust identification of peptides and proteins in complex mixtures. Peptide sequences can be identified by correlating their observed tandem mass spectra (MS/MS) with theoretical spectra of peptides from a sequence database. Unfortunately, to perform this search the charge of the peptide must be known, and current chargestate-determination algorithms only discriminate singlyfrom multiply-charged spectra: distinguishing +2doi:10.1109/csb.2005.44 dblp:conf/csb/KlammerWMN05 fatcat:7jbwx5v2vfhbbb4suj3uamy4ra