Gallbladder disease is one of the most common procedures done with more than 1.2 million cholecystectomies done annually. The technique of performing LC has undergone many changes and variations. Hence; the present study was undertaken for assessing efficacy of various techniques of Laparoscopic cholecystectomy. Subjects and Methods: A total of 90 patients were enrolled in the present study and were broadly divided into three study groups as follows: Group A: Patients who underwent single port

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... C, Group B: Patients who underwent three port LC, and Group C: Patients who underwent Four port LC. Preoperative work up included evaluation of a complete history and physical examination, and radiological examinations including abdominal ultrasound. All the patients underwent LC according to their respective groups under the hands of skilled and experienced surgeons. All the postoperative follow-up details of all the patients were recorded. Results: Significant results were obtained while comparing the mean duration of surgery among subjects of all the three study groups. No-significant results were obtained while comparing the mean duration of hospital stay and incidence of complications among subjects of the three study groups. Conclusion: All the three techniques can be used with equal efficacy among subjects of the three study groups. However; in terms of duration of surgery, three port techniques was better in comparison to other two techniques.