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Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences
Diabetic foot ulcer (DFU), with a high rate of amputation and mortality, is a serious complication of diabetes. However, the therapeutic effect of diabetic foot is poor. This study aimed to investigate the effect of CD147 on epithelial-mesenchymal transition (EMT) process in DFU and molecular mechanisms. Immunohistochemistry was used to reveal the expression of several proteins, such as CD147, E-cadherin, N-cadherin, Slug, and Phospho-RSK2 in DFU, non-diabetic refractory tissues, and wounddoi:10.11817/j.issn.1672-7347.2020.200018 pmid:33053534 fatcat:u5hdomyi6rgljpiokmzq2ac2fe