in which the plasmodia are no longer found in the general blood stream, but arc hidden away in the usually much enlarged spleen. The so-called "parasyphilitic" affections are now diagnosed by lumbar puncture in the very early stages, before the damage is so great that neither diagnosis nor treatment can avail to influence the course of the diseases. It is considered that the presence of leucocytes and an increase of globulin content are indications of the presence of cerebrospinal syphilis.