Cutaneous Manifestations of Hashimoto's Thyroiditis: A Cross-Sectional Study ORIGINAL RESEARCH

Nicely Philip, Banavasi Girisha, Tonita Noronha, Akshata Alva, Carol Christy
2016 International Journal of Contemporary Medical Research   unpublished
The interrelationship between the thyroid gland and the skin is dynamic and complex. Various studies have revealed multitude of cutaneous changes that occur in thyroid hormonal dysfunction. Hashimoto's thyroiditis is a common form of autoimmune thyroid disease. This study evaluates skin, hair and nail changes in patients diagnosed with Hashimoto's Thyroiditis. Material and Methods: 63 cases of Hashimoto's Thyroiditis, diagnosed by serum TSH and thyroid specific Auto-antibodies in serum
more » ... s in serum (Antithyroid peroxidise, anti-thyroglobulin) were included in the study. They were examined and relevant findings were documented in prestructured proforma. Study duration was one year. Results: Sixty three patients with Hashimoto's Thyroiditis were included in this study, out of which 55 were females and 8 were males. Affected age group was 21-69 years. The most common cutaneous conditions for which patients visited our OPD were for Xerosis (77%) followed by Diffuse Alopecia, Maderosis (unilateral), Acanthosis Nigricans, Melasma,Alopecia Areata and Seborrheic Dermatitis. The commonest nail changes were brittle nails (47.6%) followed by slow nail growth, longitudinal ridging, chronic paronychia and soft nails. The most common hair findings were diffuse hair fall, seen in 66% of patients, followed by coarse scalp hair. Other autoimmune conditions associated were Alopecia Areata (16%) and Vitiligo. Type 2 Diabetes mellitus was present in 13% of patients. Conclusion: Xerosis and pale old wrinkled skin formed the majority of skin manifestations among the study group. The most common hair related complaint was of Diffuse hair loss,followed by dry, coarse hair. The commonest nail change seen was brittle nails.