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Severe thalamic injury can determine a particular type of vascular dementia affecting multiple network dysfunctions, considered the central role of thalamus as a hub for afferent and efferent stimuli. A 67-year-old male patient with bilateral thalamic stroke was studied with positron emission tomography, magnetic resonance imaging, and cognitive assessment, performed at baseline and at two follow-up evaluations. A pattern primarily involving thalamo-frontal connections was observed by both PETdoi:10.3389/fneur.2019.01048 pmid:31681141 pmcid:PMC6802733 fatcat:xfqrhdi5yrcithrj6yxhty43ay