Research Advances on Effect of Adipose-derived Stem Cells on Biological Characteristics of Breast Cancer

WAN Yan, LIANG Zhijie, WEI Changyuan
2019 Zhongliu Fangzhi Yanjiu  
Stem cell-assisted transplantation technology has been widely used in superficial soft tissue defect remodeling, and has been the trend of the future in postoperative reconstruction of breast cancer. Adipose-derived stem cells(ADSCs) possess excellent abilities of proliferation, multi-differentiation, paracrine and so on, and they are very important in efficacy optimization of autologous fat grafting. However, ADSCs have been proved to promote the proliferation, epithelialization of breast
more » ... tion of breast cancer cells and the formation of new blood vessels in breast cancer in vitro, arousing a controversy about oncology safety. This review aims to outline the potential role of ADSCs in breast reconstruction and discuss their safety impact on breast cancer.
doi:10.3971/j.issn.1000-8578.2019.19.0429 doaj:aff6a1422f4d431d84fce55c6d121dc8 fatcat:2tbfqbbimnf6fowqiv2qqxn7ga