An Unusual Cause of Multiple Left Ventricle Thrombi in a Young Woman

Sofien Zayed, Rami Tlili, Fares Azaiez, Rim Hentati, Fatma Zouari, Rim Ben Romdhane
2020 Journal of Case Reports  
Antiphospholipid syndrome (APS) is a rare autoimmune disease with an increased risk of vascular occlusion and pregnancy complications. As a multisystemic disease, the heart is usually affected by direct (autoimmune action) or indirect (thrombosis) pathological mechanisms. Case Report: A 40-year-old diabetic and hypertensive woman presented with congestive heart failure. The echocardiographic exploration showed reduced left ventricle ejection fraction (20%) and diffuse wall motion abnormalities
more » ... ith multiple large thrombi in the left ventricle. The coronary angiography was normal. The APS was confirmed by positive laboratory tests (La, aCL and aß2GPI). Conclusion: The revelation of APS by cardiac manifestations, mainly cardiac thrombosis, is rarely reported in the literature, and evolution is usually unfavorable..
doi:10.17659/01.2020.0050 fatcat:377ts4r7obawbcbay6hnt5cg6m