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Antiphospholipid syndrome (APS) is a rare autoimmune disease with an increased risk of vascular occlusion and pregnancy complications. As a multisystemic disease, the heart is usually affected by direct (autoimmune action) or indirect (thrombosis) pathological mechanisms. Case Report: A 40-year-old diabetic and hypertensive woman presented with congestive heart failure. The echocardiographic exploration showed reduced left ventricle ejection fraction (20%) and diffuse wall motion abnormalitiesdoi:10.17659/01.2020.0050 fatcat:377ts4r7obawbcbay6hnt5cg6m