Etoposide as Salvage Therapy for Cytokine Storm due to COVID-19 [article]

(:Unkn) Unknown, University, My
2020
Coronavirus disease 2019 (COVID-19) has resulted in significant morbidity and mortality because of a lack of effective therapies. Therapeutic strategies under investigation target the overactive cytokine response with anti-cytokine or immunomodulators therapies. We present a unique case of severe cytokine storm resistant to multiple anti-cytokine therapies, but eventually responsive to etoposide. Thus, etoposide may have a role as salvage therapy in treatment of cytokine storm in COVID-19. To
more » ... m in COVID-19. To our knowledge, this is the first reported case of use of etoposide in COVID-19.
doi:10.34944/dspace/4135 fatcat:rthzmij5fzcbjjdt7u2y6gd25q