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Total Synthesis of (±)-Salimabromide
2018
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Total Synthesis of (±)-Salimabromide Significance: Unlike their terrestrial counterparts, myxobacteria of marine origin have remained underexplored by the scientific community. Recently, the polyketide antibiotic salimabromide was isolated from obligate marine myxobacterium Enhygromyxa salina. Magauer's team mastered the challenges associated with the preparation of this structurally demanding and biologically potent secondary metabolite. Pivotal in their approach to this bridged tetracycle
doi:10.1055/s-0037-1609605
fatcat:6wb22w2sh5gzhhdm5k3mfmegiu