The article studied rare and endemic plants scattered on the relic mountain of Sultan-Uvays. During the studies, the floristic list of the territory was also formed. Floristical studies revealed 497 species of vascular plants, belonging to 230 genera and 49 families. Investigated flora can be characterized by 1 endemic and 10 subendemic species should be included in the List of rare and endangered plants of Karakalpakistan as well as in the Red Data Book of Uzbekistan. It was found out that the

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... populations of the studied species are in normal condition. Information obtained on the distribution of rare and endemic species is used in the preparation of plans for protection measures and monitoring studies, as well as in the preparation of the next editions of the flora of Uzbekistan and the red book of the Republic of Uzbekistan.