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AbstractMethamphetamine (MA) could induce functional and structural brain alterations in dependent subjects. However, few studies have investigated resting-state activity in methamphetamine-dependent subjects (MADs). We aimed to investigate alterations of brain activity during resting-state in MADs using fractional amplitude of low-frequency fluctuation (fALFF) and regional homogeneity (ReHo). We analyzed fALFF and ReHo between MADs (n = 70) and healthy controls (HCs) (n = 84) and performeddoi:10.1038/s41598-021-87185-z pmid:33833282 pmcid:PMC8032776 fatcat:xutymur3gfc6vnsn7sv3y4357a