Experimental Simulation of Volume Repainting Technique at Proton Synchrotron in Context of Spot Scanning Proton Therapy

Mikhail Belikhin, Alexander Chernyaev, Alexander Pryanichnikov, Alexander Shemyakov, Kuzin, Maksim V. (Ed.), Schaa, Volker RW (Ed.)
2021
Reduction the influence of respiration-induced intrafractional motion of tissues is one of the main tasks of proton therapy with a scanning beam. Repainting is one of the techniques of motion compensation. It consists in multiple repeated irradiations of the entire volume or individual iso-energy layers with a dose that is a multiple of the prescribed dose. As a result, the dose is averaged, which leads to an increase in the uniformity of the dose field. Purpose: Experimental simulation of
more » ... e sequential repainting and dosimetric estimation of its capabilities in the context of spot scanning proton therapy (SSPT) using dynamic phantom. Materials and Methods: Simulation of respiration-like translational motion is performed using the non-anthropomorphic water dynamic phantom. Target of this phantom is compatible with EBT-3 films. Estimation of repainting technique is based on the analysis of average dose, dose uniformity in region of interests located within planning target volume, and dose gradients. Results: Repainting was estimated for motion with amplitudes of 2, 5, 10 mm with different number of iterations up to 10 at the prescribed dose of 6 Gy. This one increased the uniformity of the dose field from 85,9% to 96,0% at an amplitude of 10 mm and 10 iterations. Conclusions: Volume repainting improves the uniformity of dose distribution. However, the irradiation time increases, and the dose gradients deteriorate in proportion to the amplitude of motion.
doi:10.18429/jacow-rupac2021-mopsa45 fatcat:kqqhz4j7brcibkwfjx7c4hmnvq