Generalizing the Splits Equivalence Theorem and Four Gamete Condition: Perfect Phylogeny on Three State Characters [article]

Fumei Lam, Dan Gusfield, Srinath Sridhar
2009 arXiv   pre-print
We study the perfect phylogeny problem and establish a generalization of the four gamete condition (also called the Splits Equivalence Theorem) for sequences over three state characters. Our main result is that a set of input sequences over three state characters allows a perfect phylogeny if and only if every subset of three characters allows a perfect phylogeny. In establishing these results, we prove fundamental structural features of the perfect phylogeny problem on three state characters
more » ... d completely characterize the minimal obstruction sets that must occur in three state input sequences that do not have a perfect phylogeny. We further give a proof for a stated lower bound involved in the conjectured generalization of our main result to any number of states. The techniques are based on the chordal graph view of perfect phylogeny. Until this work, the notion of a conflict, or incompatibility, graph has been defined for two state characters only. Our generalization of the four gamete condition allows us to generalize the notion of incompatibility to three state characters. The resulting incompatibility structure is a hypergraph, which can be used to solve algorithmic and theoretical problems.
arXiv:0905.1417v2 fatcat:ujyl7xdub5bene7wqgkk5ufyte