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Purpose: To explore the safety and efficacy of irreversible electroporation ablation in unresectable fibrous sarcoma with 2 electrodes. Methods: A 74-year-old woman with unresectable retroperitoneal malignant fibrous sarcoma was treated with percutaneous irreversible electroporation. Four ablations were performed on the mass, which measured 7.3 Â 7.0 Â 7.5 cm, with 2 electrodes. Results: A contrast-enhanced computed tomography scan 2 months postoperatively showed that the tumor had reduced todoi:10.1177/1533034617711530 pmid:28558487 pmcid:PMC5762055 fatcat:5c2hcvs5hjclxaype66s33twru