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Here we developed a new method, called multivariate tensor-based surface morphometry (TBM), and applied it to study lateral ventricular surface differences associated with HIV/AIDS. Using concepts from differential geometry and the theory of differential forms, we created mathematical structures known as holomorphic one-forms, to obtain an efficient and accurate conformal parameterization of the lateral ventricular surfaces in the brain. The new meshing approach also provides a natural way todoi:10.1016/j.neuroimage.2009.10.086 pmid:19900560 pmcid:PMC2859967 fatcat:5uglffpjzjdipibbo5lbevm7xu