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The importance of vaccination has recently been widely recognized among Japanese people with a growing interest in vaccine. On the other hand, because vaccine is administrated to healthy people, it has had a di‹cult history due to overreaction to adverse events. With the recent rapid increase in the rate of vaccination, however, it is essential to correct the understanding of the public as to the risk and beneˆt of vaccine. Life spans around the world and infectious diseases are closelydoi:10.1248/yakushi.14-00228-7 pmid:25747223 fatcat:xy5m74fvcnfvtcwt3aqgoefxfi