Manufacture and Utilization of a Low-level Radioactive 68Ge/68Ga Generator in a Radiochemistry Laboratory Course
低レベル放射能の68Geを用いた 68Ge/68Gaジェネレータの作製と放射化学実習への応用

Kohshin Washiyama, Ryohei Amano, Tadashi Nozaki, Koji Ogawa, Kotaro Nagatsu, Minoru Sakama, Tatuo Ido, Hiroshi Yamaguchi
2015 Japanese Journal of Radiological Technology  
The low-level radioactivity of a 68 Ge/ 68 Ga generator is a suitable tool for measuring radioactive growth and decay after 68 Ga milking due to their desirable nuclear decay properties, such as the EC decay of 68 Ge with no γ-ray emission and the β + decay of 68 Ga with a weak γ-ray emission. To experience and understand radioactive equilibrium during a university laboratory course, we surveyed and tested the production of a small amount of 68 Ge and set up educational programs to manufacture
more » ... 68 Ge/ 68 Ga generator for measuring the growth and decay of 68 Ga. The irradiation of nat Ga with 25 μA of a 30 MeV proton beam from a cyclotron for 4 h yields ca. 111 MBq of 68 Ge, which was sufficient to supply to several universities. For use as the adsorbent of the generator column, particles of hydrated tin (VI) oxide were prepared from precipitated tin hydroxide gel. Repeated elution of 68 Ga from the handmade 68 Ge/ 68 Ga generator gave constant amounts of 68 Ga with acceptable breakthrough of 68 Ge. The feedback from the student's experience with the 68 Ge/ 68 Ga generator was evaluated by annual questionnaire surveys, which were given to all students taking the course every year from 2012 to 2014. It has been made clear that more than half of the students were interested in the 68 Ge/ 68 Ga generator program, and this interest increased from 54.9% in 2012 to 78.6% in 2014. A low-level radioactive 68 Ge/ 68 Ga generator is thus expected to be a suitable experimental tool for demonstrating the phenomenon of radioactivity to students in an intriguing way.
doi:10.6009/jjrt.2015_jsrt_71.10.983 pmid:26490232 fatcat:rgkmwwl6cjbe7a4b7pvrlgjlzm