Raman spectroscopic analysis of high molecular weight proteins in solution – considerations for sample analysis and data pre-processing

Drishya Rajan Parachalil, Brenda Brankin, Jennifer McIntyre, Hugh J. Byrne
2018 The Analyst  
This study explores the potential of Raman spectroscopy, coupled with multivariate regression techniques and ion exchange chromatography, to quantitatively monitor diagnostically relevant changes in high molecular weight proteins in liquid plasma.
doi:10.1039/c8an01701h pmid:30325366 fatcat:p67ha6vhprdvhjnbfl2zn4vo5e