Interaction of cisplatin with membranes of rat ehrlich ascites tumor cell

Baowei Chen, Kui Wang
1995 Chinese Journal of Cancer Research  
Quenching effects of cis-DDP on fluorescence of membranes of rat Ehrlich ascites tumor cell and binding of cis-DDP with the membranes were studied. The results indicate that cis-DDP can react with tumor cell membrane proteins. If the Pt binding sites were grouped into two types, the apparent stability canstants (K) and number of binding sites (n) are estimated.
doi:10.1007/bf02954697 fatcat:lfe6a3x2ubfxlbbaihkeak67u4