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Effect of somatostatin on renal function
BMJ (Clinical Research Edition)
Somatostatin has profound effects on both splanchnic and portal vascular beds. The effects of intravenous somatostatin (100 .tg/h) on urinary volume, effective renal plasma flow, and glomerular filtration rate were compared with the effects of a control infusion of physiological saline in six normal subjects. Renal plasma flow and glomerular filtration rate were measured by primed constant isotope infusions of iodine-125 iodohippurate and chromium-51 edetic acid. Urinary volume, renal plasmadoi:10.1136/bmj.292.6537.1701 fatcat:hhjq27dxnnhj5pnzbuwiu4ggke