Characteristics of Patients Older than 90 Years Diagnosed with Neovascular Age-related Macular Degeneration

Youn Gon Lee, Sang Yun Han, Jae Wook Han, Jong Woo Kim, Chul Gu Kim, Dong Won Lee, Jae Hui Kim
2018 Journal of the Korean Ophthalmological Society  
Purpose: To evaluate the characteristics of patients aged ≥ 90 years who were diagnosed with neovascular age-related macular degeneration (AMD). Methods: A retrospective review of medical records was performed for 44 patients aged ≥ 90 years diagnosed with neovascular AMD. History of cerebrovascular or cardiovascular disorder and visual acuity at diagnosis were assessed. Fellow eye visual acuity data were also collected. When the fellow eye visual acuity was worse than 0.5, the primary reason
more » ... he primary reason for the visual deterioration was identified. Results: The mean patient age was 91.5 ± 1.5 years (range: 90-95 years). Ten (22.7%) patients had histories of cerebrovascular or cardiovascular disorders. The mean logarithm of the minimal angle of resolution (logMAR) of visual acuity was 1.11 ± 0.51 and the visual acuity was worse than 0.1 in 20 eyes (45.5%). The fellow eye visual acuity was worse than 0.5 in 26 eyes (59.1%). The primary reason was neovascular or atrophic AMD in 23 eyes (88.5%). Conclusions: The incidence of cerebrovascular or cardiovascular disorders was relatively high in patients aged ≥ 90 years. Patients also had poor visual acuity at diagnosis and a high incidence of fellow eye visual deterioration. These systemic conditions should be considered when treating these patients. Additionally, a regular ophthalmic examination is recommended for the early detection of these disorders. J Korean Ophthalmol Soc 2018;59 (5) :444-450 노화와 관련된 망막의 변화가 발병에 큰 영 향을 미치는 것으로 알려져 있다. 국내 연간 발병률은 40세 이상 성인 10,000당 약 3명 정도인데, 70세 이상에서 특히 그 발병률이 증가하는 것으로 나타나, 3 인구의 고령화와 함 께 향후 환자들이 증가할 가능성이 높은 질환이다. 국내 환자를 대상으로 한 연구 3 에서 습성 나이관련황반 변성을 처음 진단받은 환자들의 연령은 70대에 가장 많이 분포하였으며, 발병률의 경우 70-80대에 가장 높은 경향을 보였다. 90대 이상의 초고령 환자의 경우 그 숫자는 60-80 대에 비해 적으나 발병률은 60대와 크게 차이나지 않는 결 과를 보였다. 3 해외 보고에 따르면 90세 이상의 환자는 전 체 습성 나이관련황반변성 환자의 약 7% 정도를 차지하는
doi:10.3341/jkos.2018.59.5.444 fatcat:jg3fori52fb2blqbwbwizoisq4