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Serum Haptoglobin: A Novel Marker of Adiposity in Humans
Journal of Clinical Endocrinology and Metabolism
Haptoglobin (Hp) is a glycoprotein involved in the acute phase response to inflammation. Our previous findings indicate that Hp mRNA and protein are present in the adipose tissue of rodents and that Hp gene expression is up-regulated in obese models. The aim of the present study was to establish whether Hp could be considered a marker of obesity in humans. In 312 subjects, serum Hp was correlated directly with body mass index (BMI), leptin, C-reactive protein (CRP), and age. In a multivariatedoi:10.1210/jc.2003-031965 pmid:15181041 fatcat:htvsat25mrg6vap2i3xdgv4pei