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The study examined the relationship of capital structure to profitability of quoted firms in Nigeria. The study was based on a panel data set from 1996 to 2010 comprising sixty non – financial companies. The study specified two panel regression models. Two profitability measures: Net Profit Margin (NPM) and Operating Profit Margin (OPM) were taken as the dependent variables respectively. The principal explanatory variable for each of the models was Debt Ratio (DR). The results of the studydoi:10.18533/ijbsr.v3i3.59 doaj:975db061a0b94315a12aa6576291f1ef fatcat:pnxq77ayxnfqvk4o24t3iallra